CDC27 (Protein | Antibody | cDNA Clone | ELISA Kit)

All CDC27 reagents are produced in house and quality controlled, including 15 CDC27 Gene, 1 CDC27 qPCR. All CDC27 reagents are ready to use.

CDC27 cDNA Clone (15)

CDC27 qPCR Primer (1)

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CDC27 Related Research Area

CDC27 Background

Cdc27, a component of the anaphase-promoting complex (APC/C), as a novel binding partner of MCPH1. APC/C is an E3 ubiquitin ligase that controls the cell cycle. A combination of in vitro and in vivo experiments revealed that the interaction between MCPH1 and Cdc27 is dependent on the phosphorylation of Cdc27 and is mediated by the C-terminal BRCT domains of MCPH1.

CDC27 References

  • Singh N, Wiltshire TD, Thompson JR, Mer G, Couch FJ. Molecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting Complex. The Journal of Biological Chemistry. 2012;287(4):2854-2862.